Labs – Integrated Program in Biochemistry

Richard M. Amasino

Regulation of plant development; mechanisms of floral induction

Alan D. Attie

Genetics of diabetes, beta-cell biology, lipid metabolism

Jon Audhya

Regulation of membrane transport during development and disease

Sebastian Y. Bednarek

Plant cell biology; intracellular protein trafficking, membrane biogenesis

David A. Brow

RNA biology and gene expression in eukaryotes

Andrew R. Buller

Protein engineering and biocatalysis

Samuel E. Butcher

Structural biology of RNA interactions that regulate gene expression

Zachary T. Campbell

RNA control in pain sensing neurons

Jason R. Cantor

Studies human cell biology and how it is influenced by environmental factors with relevance to cancer and immunology

Silvia Cavagnero

Protein structure, folding, dynamics and aggregation in the cell; role of ribosome and molecular chaperones

Snehal N. Chaudhari

Interactions of the gut microbiome with the host; intestinal metabolism in health and disease

Joshua J. Coon

Bioanalytical chemistry, mass spectrometry and proteomics

Michael M. Cox

Molecular biology and enzymology of genetic recombination and DNA repair

Scott M. Coyle

Understanding and engineering microscale molecular and cellular machines

Gheorghe Craciun

Mathematical and computational methods in biology

Elizabeth A. Craig

The function of molecular chaperones in the cell - Folding and remodeling of proteins

John M. Denu

Mechanisms of chromatin dynamics, epigenetic, metabolism and signaling

Feyza Engin

Cellular stress responses, organelle dysfunction and interaction, beta cell function and survival, diabetes

Jing Fan

Dynamical metabolic regulation, immunometabolism, metabolic underpinnings of cell function

Brian G. Fox

Biochemical, catalytic, and spectroscopic studies of redox active enzymes; protein engineering

Catherine A. Fox

Conservation and diversity in mechanisms that control the inheritance and expression of eukaryotic chromosomes

Paul D. Friesen

Molecular biology of eukaryotic DNA viruses, gene expression regulation, apoptosis, retrotransposons

Andrea Galmozzi

Identification of adipocyte functional pathways using chemoproteomics methods

Samuel H. Gellman

Proteins and protein-like molecules: design, synthesis, structure and function

Timothy Grant

Studying the structure and dynamics of biological macromolecules using cryo-EM

Melissa M. Harrison

Transcriptional regulation during development

Katherine Henzler-Wildman

Dynamics and function of integral membrane proteins, secondary active transport, ion channels

Gaelen Hess

High-throughput functional genomics to investigate DNA repair and pathogenic effectors

Hazel M. Holden

Structure and function of enzymes

Aaron A. Hoskins

Mechanistic studies of eukaryotic RNA processing using chemical, genetic, and biophysical approaches

Christina M. Hull

Human fungal pathogen development and pathogenesis

James L. Keck

Structural mechanisms of genome maintenance

Patricia J. Kiley

Molecular genetics and biochemistry of oxygen regulated gene expression and transcription activation

Judith Kimble

Molecular regulation of animal development

Robert N. Kirchdoerfer

Structural and biochemical exploration of RNA virus entry and replication

Robert Landick

RNA polymerase structure/function; regulation of transcript elongation in bacteria and humans

Peter W. Lewis

Mechanisms of chromatin assembly, gene silencing, and epigenetic inheritance

Ci Ji Lim

Mechanism of telomere maintenance; Structure-function studies of biological machines by cryo-EM and single-molecule imaging

Matthew J. Merrins

Regulation of nutrient metabolism and hormone secretion in pancreatic islets

Deane F. Mosher

Extracellular matrix; cell adhesion

James M. Ntambi

Genetic regulation of metabolism: the stearoyl-CoA desaturase genes

Ann C. Palmenberg

Biology and Biochemistry of RNA picornaviruses

Andrea Putnam

Function and regulation of RNA condensates in development

John Ralph

Plant cell wall structure, biosynthesis and utilization

Srivatsan Raman

Understanding and designing biomolecular systems using high-throughput functional assays

Ivan Rayment

Molecular basis of protein function

M. Thomas Record, Jr.

Biophysical chemistry of proteins, nucleic acids and their interactions

Chad M. Rienstra

Development and application of solid-state NMR spectroscopy to protein, lipid and small molecule structure and dynamics

Philip A. Romero

Protein engineering, computational biology, high-throughput technology

Alessandro Senes

Biochemical and computational studies of membrane protein interactions

Michael D. Sheets

RNA regulation of cell fate and function

Judith Simcox

Inter-organ communication through lipid derived metabolites

Michael R. Sussman

Signal transduction in eukaryotes, genomic technologies, membrane receptors and ion transporters

Ophelia S. Venturelli

Understanding and engineering microbial communities across space and time

Tina Wang

Protein engineering, directed evolution, and protein folding

Amy M. Weeks

Spatially-resolved mapping of post-translational modifications; protein engineering; chemoproteomics

Elizabeth R. Wright

3D structure of viruses, bacteria, and mammalian cells by cryo-electron microscopy

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