Biomolecular Folding & Interactions

Harrison, Melissa M.

Transcriptional regulation during development

Mechanistic studies of eukaryotic RNA processing using chemical, genetic, and biophysical approaches

Human fungal pathogen development and pathogenesis

Structural mechanisms of genome maintenance

Molecular genetics and biochemistry of oxygen regulated gene expression and transcription activation

Structural and biochemical exploration of RNA virus entry and replication

RNA polymerase structure/function; regulation of transcript elongation in bacteria and humans

Mechanisms of chromatin assembly, gene silencing, and epigenetic inheritance

Understanding and designing biomolecular systems using high-throughput functional assays

3D structure of viruses, bacteria, and mammalian cells by cryo-electron microscopy