Biomolecular Folding & Interactions

Hoskins, Aaron A.

Mechanistic studies of eukaryotic RNA processing using chemical, genetic, and biophysical approaches

Human fungal pathogen development and pathogenesis

Structural mechanisms of genome maintenance

Molecular genetics and biochemistry of oxygen regulated gene expression and transcription activation

Structural and biochemical exploration of RNA virus entry and replication

RNA polymerase structure/function; regulation of transcript elongation in bacteria and humans

Biochemical mechanisms of chromatin regulation, genome stability, and cancer

Understanding and designing biomolecular systems using high-throughput functional assays

3D structure of viruses, bacteria, and mammalian cells by cryo-electron microscopy

Understanding and engineering microscale molecular and cellular machines