Unraveling the network of molecules that influence COVID-19 severity

While most COVID-19 cases are asymptomatic or mild, severe complications associated with acute respiratory distress have led to more than one million deaths worldwide in just several months. Researchers from the Morgridge Institute for Research, the University of Wisconsin-Madison, and Albany Medical College sought to better understand the molecular factors that drive the severity of …

Pediatric cancers share stalled gene-managing enzyme

A wildly out-of-place protein leads to haywire cells in a particularly troublesome type of rare early childhood cancer, according to University of Wisconsin–Madison researchers. Found in the base of the brain, posterior fossa type A ependymomas tumors are difficult to remove via surgery and prove fatal in more than a quarter of children within five …

Scott Coyle Awarded 2020 Packard Fellowship

Scott M. Coyle, a University of Wisconsin–Madison assistant professor of biochemistry, has been named a 2020 Packard Foundation Fellow in Science and Engineering. Coyle, whose research focuses on understanding and engineering microscale molecular and cellular machines, is one of 20 early career scientists from across the United States to be awarded this year’s Packard Fellowship. …

New national imaging center has potential to transform medicine

MADISON — A national research initiative announced today will place the University of Wisconsin–Madison at the forefront of a revolution in imaging fostered by cryo-electron microscopy and cryo-electron tomography — technologies that can illuminate life at the atomic scale. The National Institutes of Health will provide $22.7 million over six years to create a national research …

IPiB Welcomes Incoming Class for 2020-21 Year

The Integrated Program in Biochemistry (IPiB) is pleased to welcome its newest class of incoming students. The 2020 cohort is comprised of 14 students from across the country. Students hail from such undergraduate institutions as Smith College, Texas A&M, and Boston College, and bring with them diverse experience to adapt to the changes that come …

Students Recognized by NSF Graduate Research Fellowship Program

Three students in the Integrated Program in Biochemistry (IPiB) have been recognized by the National Science Foundation (NSF) Graduate Research Fellowship Program. Christine Hustmyer, a graduate student in Professor Robert Landick’s lab, was awarded a 2020 Graduate Research Fellowship. Jacob Rapp, a graduate student in the lab of Assistant Professor Phil Romero, and John Ahn, …

Coon Honored with Kellett Mid-Career Award

Josh Coon from Biomolecular Chemistry has been honored with a Kellett Mid-Career Award, as one of 10 distinguished campus researchers receiving them this year. The Mid-Career award was created to provide needed support and encouragement to faculty at a critical stage of their careers. The Kellett Mid-Career awards are made possible by the impressive research efforts …

Harrison Earns 2020 Romnes Professorship

Biomolecular Chemistry professor Melissa Harrison has been honored with a Romnes Named Professorship, as one of 11 distinguished campus researchers receiving them this year. This program, funded by WARF in recognition of the leadership of the late WARF Trustee President H. I. Romnes, is designed to bridge the gap between the Research Committee’s initial research …

Engin discovery: deleting a gene prevents Type 1 diabetes in mice

Removing a gene from the cells that produce insulin prevents mice from developing Type 1 diabetes by sparing the cells an attack from their own immune system, a new UW–Madison study shows. The cellular sleight of hand may suggest ways to prevent Type 1 diabetes in high-risk individuals, as well as other diseases in which …