Metabolism & Endocrinology

Stefely, Jonathan

Comparative metabolism – from pathogenic amoeba to humans – to uncover both new biology and new drug targets

Deorphanizing biochemical pathways that regulate nutrient metabolism in mammals

Interactions of the gut microbiome with the host; intestinal metabolism in health and disease

Dynamical metabolic regulation, immunometabolism, metabolic underpinnings of cell function

Identification of adipocyte functional pathways using chemoproteomics methods

Cellular stress responses, organelle dysfunction and interaction, beta cell function and survival, diabetes

Genetic regulation of metabolism: the stearoyl-CoA desaturase genes

Inter-organ communication through lipid derived metabolites

Genetics of diabetes, beta-cell biology, lipid metabolism, and diet outcome