Researchers at the University of Wisconsin–Madison have developed a novel strategy to reprogram cells from one type to another in a more efficient and less biased manner than previous methods.
The ability to convert cells from one type to another holds great promise for engineering cells and tissues for therapeutic application, and the new Wisconsin study could help speed research and bring the technology to the clinic faster.
The new approach, published this week (Dec. 5, 2016) in the Proceedings of the National Academy of Sciences (PNAS), uses a library of artificial transcription factors to switch on genes that convert cells from one type to another.
To read more about this work, see the link below.