New research on transcriptional pausing, which helps control gene expression in cells, will aid in the understanding of the enzyme RNA polymerase — a key player in the process and an important drug target.
The lab of IPiB faculty member Robert Landick has provided this new insight on the mechanism underlying the control of gene expression in all living organisms in a study published today (Jan. 8) in eLife.
The findings could ultimately improve the understanding of how certain antibacterial drugs work against the enzyme RNA polymerase (RNAP) in treating conditions such as Clostridium difficile infections and tuberculosis.
To read more of this research, see the link below.