Research Faculty

Sheets, Michael D.

RNA regulation of cell fate and function

Inter-organ communication through lipid derived metabolites

Comparative metabolism – from pathogenic amoeba to humans – to uncover both new biology and new drug targets

Signal transduction in eukaryotes, genomic technologies, membrane receptors and ion transporters

Protein engineering, directed evolution, and protein folding

Predicting biomolecular dynamics; understanding roles of dynamics in function, evolution, design

Spatially-resolved mapping of post-translational modifications; protein engineering; chemoproteomics

Deorphanizing biochemical pathways that regulate nutrient metabolism in mammals

3D structure of viruses, bacteria, and mammalian cells by cryo-electron microscopy

Protein-protein interactions at the host-pathogen interface