Faculty

Regulation of plant development; mechanisms of floral induction

Genetics of diabetes, beta-cell biology, lipid metabolism

Regulation of membrane transport during development and disease

Plant cell biology; intracellular protein trafficking, membrane biogenesis

RNA biology and gene expression in eukaryotes

Protein engineering and biocatalysis

Structural biology of RNA interactions that regulate gene expression

RNA control in pain sensing neurons

Studies human cell biology and how it is influenced by environmental factors with relevance to cancer and immunology

Protein structure, folding, dynamics and aggregation in the cell; role of ribosome and molecular chaperones

Interactions of the gut microbiome with the host; intestinal metabolism in health and disease

Bioanalytical chemistry, mass spectrometry and proteomics

Understanding and engineering microscale molecular and cellular machines

Mathematical and computational methods in biology

Mechanisms of chromatin dynamics, epigenetic, metabolism and signaling

Cellular stress responses, organelle dysfunction and interaction, beta cell function and survival, diabetes

Dynamical metabolic regulation, immunometabolism, metabolic underpinnings of cell function

Biochemical, catalytic, and spectroscopic studies of redox active enzymes; protein engineering

Conservation and diversity in mechanisms that control the inheritance and expression of eukaryotic chromosomes

Molecular biology of eukaryotic DNA viruses, gene expression regulation, apoptosis, retrotransposons

Identification of adipocyte functional pathways using chemoproteomics methods

Proteins and protein-like molecules: design, synthesis, structure and function

Molecular basis of bioenergetic systems involved in photosynthesis

Studying the structure and dynamics of biological macromolecules using cryo-EM

Transcriptional regulation during development

Dynamics and function of integral membrane proteins, secondary active transport, ion channels

High-throughput functional genomics to investigate DNA repair and pathogenic effectors

Structure and function of enzymes

Mechanistic studies of eukaryotic RNA processing using chemical, genetic, and biophysical approaches

Human fungal pathogen development and pathogenesis

Structural mechanisms of genome maintenance

Molecular genetics and biochemistry of oxygen regulated gene expression and transcription activation

Structural and biochemical exploration of RNA virus entry and replication

RNA polymerase structure/function; regulation of transcript elongation in bacteria and humans

Mechanisms of chromatin assembly, gene silencing, and epigenetic inheritance

Human telomere replication and maintenance

Regulation of nutrient metabolism and hormone secretion in pancreatic islets

Discovery, characterization, and evolution of enzymes for biocatalysis and chemical biology

Genetic regulation of metabolism: the stearoyl-CoA desaturase genes

Function and regulation of RNA condensates in development

Understanding and designing biomolecular systems using high-throughput functional assays

Molecular basis of protein function

Development and application of solid-state NMR spectroscopy to protein, lipid and small molecule structure and dynamics

Biochemical and computational studies of membrane protein interactions

RNA regulation of cell fate and function

Inter-organ communication through lipid derived metabolites

Signal transduction in eukaryotes, genomic technologies, membrane receptors and ion transporters

Protein engineering, directed evolution, and protein folding

Predicting biomolecular dynamics; understanding roles of dynamics in function, evolution, design

Spatially-resolved mapping of post-translational modifications; protein engineering; chemoproteomics

3D structure of viruses, bacteria, and mammalian cells by cryo-electron microscopy

Protein-protein interactions at the host-pathogen interface